Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 8tqi
Q-score: 0.499
Suryadevara N, Otrelo-Cardoso AR, Kose N, Hu YX, Binshtein E, Wolters R, Drew-Bear J, Handal LS, Carnahan RH, Moscona A, Jardetzky TS, Crowe Jr JE
To Be Published
- Hpiv3 hn in complex with rpiv3-23 and rpiv3-28 fabs (Complex from Human respirovirus 3)
- Light chain fab rpiv3-28 (23 kDa, Protein from Homo sapiens)
- Hemagglutinin-neuraminidase (50 kDa, Protein from Human respirovirus 3)
- Heavy chain fab rpiv3-28 (23 kDa, Protein from Homo sapiens)
- Heavy chain fab rpiv3-23 (24 kDa, Protein from Homo sapiens)
- Light chain fab rpiv3-23 (23 kDa, Protein from Homo sapiens)
- Recombinant rpiv3-23 fab (Complex from Homo sapiens)
- Recombinant rpiv3-28 fab (Complex from Homo sapiens)
- Hemagglutinin-neuraminidase glycoprotein (Complex from Human respirovirus 3)
Human parainfluenza virus type 3 prefusion F trimer in complex with rPIV3-18 Fab
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8tqk
Q-score: 0.451
Suryadevara N, Otrelo-Cardoso AR, Kose N, Hu YX, Binshtein E, Wolters R, Drew-Bear J, Handal LS, Carnahan RH, Moscona A, Jardetzky TS, Crowe Jr JE
To Be Published
- Fusion glycoprotein f0 (57 kDa, Protein from Human respirovirus 3)
- Fusion glycoprotein f0 (Complex from Human respirovirus 3)
- Rpiv3-18 heavy chain (Complex from Homo sapiens)
- Rpiv3-18 light chain (Complex from Homo sapiens)
- Hpiv3 prefusion f trimer in complex with rpiv3-18 fab (Complex from Human respirovirus 3)
- Heavy chain fab rpiv3-18 (23 kDa, Protein from Homo sapiens)
- Light chain fab rpiv3-28 (23 kDa, Protein from Homo sapiens)
RSV F trimer bound to RSV-199 Fab
Resolution: 2.46 Å
EM Method: Single-particle
Fitted PDBs: 8dzw
Q-score: 0.569
Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe Jr JE
Cell Host Microbe (2023) 31 pp. 1288-1300.e6 [ DOI: doi:10.1016/j.chom.2023.07.002 Pubmed: 37516111 ]
- Rsv fusion protein (53 kDa, Protein from Human respiratory syncytial virus A2)
- Rsv fusion protein complex with rsv-199 fab (Complex from Human respiratory syncytial virus A2)
- Rsv-199 heavy chain protein (24 kDa, Protein from Homo sapiens)
- Rsv-199 light chain protein (22 kDa, Protein from Homo sapiens)
HMPV F monomer bound to RSV-199 Fab
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 8e2u
Q-score: 0.457
Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe Jr JE
Cell Host Microbe (2023) 31 pp. 1288-1300.e6 [ DOI: doi:10.1016/j.chom.2023.07.002 Pubmed: 37516111 ]
- Mpv fusion protein complex with rsv-199 fab (Complex from Human metapneumovirus)
- Rsv-199 heavy chain (24 kDa, Protein from Homo sapiens)
- Fusion glycoprotein f0 (47 kDa, Protein from Human metapneumovirus A)
- Rsv-199 light chain (22 kDa, Protein from Homo sapiens)
Resolution: 3.33 Å
EM Method: Single-particle
Fitted PDBs: 8eay
Q-score: 0.403
Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe Jr JE
Cell Host Microbe (2023) 31 pp. 1288-1300.e6 [ DOI: doi:10.1016/j.chom.2023.07.002 Pubmed: 37516111 ]
- 4i3 light chain protein (11 kDa, Protein from Homo sapiens)
- Mpv fusion protein complex with 4i3 fab (Complex from Human metapneumovirus)
- Fusion glycoprotein f0 (45 kDa, Protein from Human metapneumovirus A)
- 4i3 heavy chain protein (13 kDa, Protein from Homo sapiens)
HMPV F dimer bound to RSV-199 Fab
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 8ebp
Q-score: 0.426
Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe Jr JE
Cell Host Microbe (2023) 31 pp. 1288-1300.e6 [ DOI: doi:10.1016/j.chom.2023.07.002 Pubmed: 37516111 ]
- Mpv fusion protein complex with rsv-199 fab (Complex from Human metapneumovirus)
- Rsv-199 heavy chain protein (24 kDa, Protein from Homo sapiens)
- Rsv-199 light chain protein (22 kDa, Protein from Homo sapiens)
- Fusion glycoprotein f0 (47 kDa, Protein from Human metapneumovirus A)
Structure of OC43 spike in complex with polyclonal Fab1 (Donor 269)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7sb3
Q-score: 0.496
Bangaru S, Antanasijevic A, Kose N, Sewall LM, Jackson AM, Suryadevara N, Zhan X, Torres JL, Copps J, de la Pena AT, Crowe Jr JE, Ward AB
Sci Adv (2022) 8 pp. eabn2911-eabn2911 [ DOI: doi:10.1126/sciadv.abn2911 Pubmed: 35507649 ]
- Spike protein (151 kDa, Protein from Human coronavirus OC43)
- Human polyclonal fab model with polyalanine backbone - heavy chain (10 kDa, Protein from Homo sapiens)
- Sapienic acid (254 Da, Ligand)
- Structure of oc43 spike in complex with polyclonal fab1 (donor 269) (Complex from Human coronavirus OC43)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of OC43 spike in complex with polyclonal Fab2 (Donor 1412)
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 7sb4
Q-score: 0.302
Bangaru S, Antanasijevic A, Kose N, Sewall LM, Jackson AM, Suryadevara N, Zhan X, Torres JL, Copps J, de la Pena AT, Crowe Jr JE, Ward AB
Sci Adv (2022) 8 pp. eabn2911-eabn2911 [ DOI: doi:10.1126/sciadv.abn2911 Pubmed: 35507649 ]
- Spike protein (151 kDa, Protein from Human coronavirus OC43)
- Structure of oc43 spike in complex with polyclonal fab2 (donor 1412) (Complex from Human coronavirus OC43)
- Sapienic acid (254 Da, Ligand)
- Human polyclonal fab model with polyalanine backbone - heavy chain (9 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of OC43 spike in complex with polyclonal Fab3 (Donor 1412)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7sb5
Q-score: 0.379
Bangaru S, Antanasijevic A, Kose N, Sewall LM, Jackson AM, Suryadevara N, Zhan X, Torres JL, Copps J, de la Pena AT, Crowe Jr JE, Ward AB
Sci Adv (2022) 8 pp. eabn2911-eabn2911 [ DOI: doi:10.1126/sciadv.abn2911 Pubmed: 35507649 ]
- Spike protein (151 kDa, Protein from Human coronavirus OC43)
- Palmitic acid (256 Da, Ligand)
- Human polyclonal fab model with polyalanine backbone - heavy chain (9 kDa, Protein from Homo sapiens)
- Structure of oc43 spike in complex with polyclonal fab3 (donor 1412) (Complex from Human coronavirus OC43)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of OC43 spike in complex with polyclonal Fab4 (Donor 269)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7sbv
Q-score: 0.544
Bangaru S, Antanasijevic A, Kose N, Sewall LM, Jackson AM, Suryadevara N, Zhan X, Torres JL, Copps J, de la Pena AT, Crowe Jr JE, Ward AB
Sci Adv (2022) 8 pp. eabn2911-eabn2911 [ DOI: doi:10.1126/sciadv.abn2911 Pubmed: 35507649 ]
- Spike protein (151 kDa, Protein from Human coronavirus OC43)
- Human polyclonal fab model with polyalanine backbone - heavy chain (9 kDa, Protein from Homo sapiens)
- Sapienic acid (254 Da, Ligand)
- Structure of oc43 spike in complex with polyclonal fab4 (donor 269) (Complex from Human coronavirus OC43)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)